This is in accordance with observations in potential CeD patients who not only lack IL-15 and stress molecules expression on intestinal tissue cells, but also do not display an accumulation of intraepithelial cytotoxic T lymphocytes with an active killer phenotype, as seen in active CeD patients, despite the development of an inflammatory CD4 T cell response (25). The gene discussed is CD4; the disease is cranioectodermal dysplasia.