KLRD1 and cranioectodermal dysplasia: However, intraepithelial lymphocytes from CeD patients were found to undergo extensive NK cell-like reprograming, downregulating expression of the inhibitory CD94/NKG2A receptor and upregulating expression of the activating CD94/NKG2C and NKG2D receptors (78, 79, 133, 134).