Compared with the normal CD4 group, more patients in the abnormal CD4 group were older (p<0.001), had a higher proportion of hypertension (p=0.008), lower CD8+ T cell counts (p<0.001), lactate dehydrogenase (LDH) elevation (p<0.001), received treatment with glucocorticoid (p<0.001), intravenous immunoglobulin (IVIG) (p<0.001) and Tα1 (p=0.001). The gene discussed is CD8A; the disease is hypertensive disorder.