GRN and frontotemporal dementia: Evaluations of the safety, tolerability and efficacy of anti-sortilin monoclonal antibody AL001 in GRN-FTD patients are underway in a Phase II trial (INFRONT-2, ClinicalTrials.gov identifier: NCT03987295), and as of July 2020, a Phase III trial (INFRONT-3, ClinicalTrials.gov identifier: NCT04374136).