Recently, Renu et al. (2020) developed subunit chitosan NP based vaccine by using immunogenic outer membrane proteins (OMPs) and flagellin (F) protein (OMPs-F-CS NPs) of Salmonella. Oral immunization of layer chickens with OMP-F-CS NPs led to localization of the nanovaccine in ileal Peyer’s patches and induced significantly higher OMP-specific mucosal IgA production as well as lymphocyte proliferation response and reduced salmonellosis in poultry (Renu et al., 2020). This evidence concerns the gene OMP and salmonellosis.