In our study, we have detected the level of serum ALT and AST in CCl4/BDL-induced hepatic fibrosis mice, and the results suggested that SolB, WeD or the combination of SolB and WeD treatment reversed the increase in ALT and AST serum levels induced by CCl4 or BDL, suggesting that the treatment reduced hepatocyte injury in vivo. This evidence concerns the gene GPT and Hepatic fibrosis.