Previously, it has been reported that TRP channels including TRPC1, TRPC6, TRPM2, TRPM3, TRPM7, TRPM8, TRPV1, and TRPV2 are overexpressed in GBM patients, implying the contribution of TRP channels in the progression of GBM (Alptekin et al., 2015). This evidence concerns the gene TRPM8 and glioblastoma.