GOT2 and cancer: Thus, activation of lipid biosynthesis and lipid remodeling has been suggested as a common feature of cancer cells and overexpression of several proteins involved in lipid metabolism, such as fatty acid-binding protein (Morgan et al. 2008), fatty acid synthase (Flavin et al. 2010a, b; SHAH et al. 2006), Caveolin-1 (Freeman et al. 2012) or fatty acid elongase 7 (Tamura et al. 2009) have been associated with tumorigenesis.