PCGF1 and rectum adenocarcinoma: We first analysed the expression of PCGF1-6 in various types of tumours using the Gene Expression Display Server (GEDS) database and found that PCGF1 in tumour tissues is generally elevated compared with that in normal controls, including colorectal READ (rectum adenocarcinoma) and COAD (colon adenocarcinoma) (Fig. 1A and Supplementary Fig. 1).