Finally, the ratios of pro-/anti-inflammatory cytokines are significantly lower in AML with highly expressing of ITGAM and lncRNA ITGB2-AS1 (expression levels > median) than in those lowly expressing of ITGAM and lncRNA ITGB2-AS1 (expression levels < median) (P < 0.001) (Figure 13D). This evidence concerns the gene ITGB2 and acute myeloid leukemia.