HCP5 and hepatocellular carcinoma: The results demonstrated that HCP5 knockdown in Hep3B and HCCLM3 cells resulted in alleviating the cell metastatic and invasive quantities (**p<0.01, ***P<0.001, Figure 2D, 2E), which indicated that the presence of HCP5 could functionally augment the metastatic and invasive abilities in HCC.