AntiOxCIN4 treatment increased p53 mRNA levels in fibroblasts from healthy controls (Fig. 8A), while GA binding protein transcription factor subunit alpha 1 (GABPA1) (Fig. 8B), activating transcription factor 4 (ATF4) (Fig. 8C), heat shock protein family A (Hsp70) member 9 (HSPA9) (Fig. 8D), DNA damage-inducible transcript 3 (CHOP) (Fig. 8F) and mitochondrial Lon peptidase 1 (LONP1) (Fig. 8G) mRNA levels were increased in fibroblasts from sPD patients treated with AntiOxCIN4. The gene discussed is DDIT3; the disease is Platelet storage pool disease.