Pathway enrichment analyses applied on the GWAS summary results have demonstrated that polygenic hypertriglyceridemia is enriched with known mechanisms related to triglyceride metabolism, such as the regulation of LPL, acylglycerol homeostasis, cholesterol transport and storage, and triglyceride-rich lipoprotein metabolism, transportation, and catabolism. Here, LPL is linked to hypertriglyceridemia.