Based on previous case–control studies, alanine aminotransferase (ALT), gamma‐glutamyl transferase (GGT) and aspartate aminotransferase (AST) are elevated in approximately 90% of cases diagnosed with HCC, while serum bilirubin or alkaline phosphatase (ALP) levels are elevated in more than half of cases.10 This evidence concerns the gene GPT and hepatocellular carcinoma.