Given the heterogeneous expression of antigens on glioblastomas, Hegde et al28 created a CAR‐That joins a HER2‐binding ScFv and an IL13Rα2‐binding IL‐13 mutein to make a tandem CAR exodomain (TanCAR) and a CD28.ζ endodomain. The gene discussed is ERBB2; the disease is glioblastoma.