ELK1 and colorectal carcinoma: In conclusion, our study revealed that glycolysis-related lncRNA MIR17HG functioned as a ceRNA in promoting CRC cell glycolysis and CRLM; moreover, the accumulated lactate could result in MIR17HG expression via the p38/Elk-1 pathway, forming a positive feedback loop between glycolysis and MIR17HG.