pT73 Rab10 levels were not significantly different in any group, but when normalized for variations in total LRRK2 levels, we observed a significant elevation in LRRK2 G2019S carriers with PD compared to sporadic PD patients and in healthy LRRK2 G2019S carriers compared to non-carriers (Fig. 5C,D; Supplementary Table 3). Here, LRRK2 is linked to Parkinson disease.