We utilized genomic data from over 25,000 solid tumors sequenced by MSK-IMPACT to generate a list of 826 exons from 129 genes encompassing the most recurrent oncogenic mutations; variants that are targets of approved or investigational therapies based on OncoKB, an in-house, institutional knowledge base of variant annotations22; frequently mutated exons; entire kinase domains of targetable receptor tyrosine kinases; and all coding exons of selected tumor suppressor genes. The gene discussed is NTRK1; the disease is neoplasm.