SAP serum levels were similar in IPA patients (18.6 ± 1.2 μg/ml, n = 20) compared to controls (16.6 ± 1.3 μg/ml, n = 14; P = 0.2), whereas higher amounts were present in BALFs (65.7 ± 26.4 ng/ml, n = 9; vs. 2.6 ± 0.7 ng/ml, n = 7; P = 0.0007) (Fig. 7c). The gene discussed is APCS; the disease is Ito hypomelanosis.