CD8A and esophageal squamous cell carcinoma: Enumeration of immune infiltrates using a deconvolution method (CIBERSORT, ref. 38) showed similar trend: EAC and ESCC had lower abundance of infiltrating T cells and CD8 T cells than LUAD and LUSC, while PSCCE had significantly even lower abundances than ESCC and EAC (both P < 0.001, Wilcoxon rank-sum test, Fig. 6b).