Therefore, while the statistical significance of observing two deleterious pzDNMs in SRCAP and the predicted deleteriousness of the p.Leu696Phe variant indicates this gene as a good candidate gene whose deleterious pzDNMs are associated with BD, there is some ambiguity especially about the pathogenicity of the p.Arg971Cys variant. Here, SRCAP is linked to Behcet disease.