These phenotypes were all reversed by AFAP1-AS1 silencing in the shlncRNA–AFAP1-AS1 + miR-2110-inhibitor group (Fig. 5; group 3 vs. group 4), which did not significantly differ from the NC group in tumor size and growth rate (Fig. 5; group 1 vs. group 4). This evidence concerns the gene PTGDR and neoplasm.