It will be of interest to determine the precise localization (e.g., T cell zones or subcapsular sinus) occupied by CD69+ CD103+ mLN Trm in general and if this distribution is altered for 4M vs 1M Trm as their localization could be important in the control of virus infections entering the mLN (Reynoso et al., 2019). Here, ITGAE is linked to viral infectious disease.