This is because cytotoxic cells, which form the majority of CD8\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$^{+}$$\end{document}+ cells, bind to MHC-I in order to eliminate tumour cells. This evidence concerns the gene CD8A and neoplasm.