EGF and neoplasm: Epidermal growth factor and GE11 peptides on HEK293-Exos recognize epidermal growth factor ligand on tumor cells, enabling the carrier to target tumors, and then miR-204-5p effectively inhibited tumor growth in mice, increased apoptosis induced by 5-fluorouracil, and reversed drug resistance to chemotherapy (Yao et al., 2020).