Cavin3 may represent a promising therapeutic target in breast cancer through its ability to act both inside and outside of caveolae, by modulating specific signaling pathways (Hernandez et al., 2013) and by interacting with and modulating the expression of many proteins such as BRCA1, as shown here, and PP1alpha as previously described (McMahon et al., 2019). The gene discussed is CAVIN3; the disease is breast cancer.