Finally, the expression levels of many dnCRTC-regulated genes were significantly higher in human TCGA lung cancers harboring LKB1 mutations, particularly in lung adenocarcinomas (Cancer Genome Atlas Research Network, 2014; Ding et al., 2008; Gao et al., 2013; Figure 4—figure supplement 3). The gene discussed is STK11; the disease is lung adenocarcinoma.