THBS4 and bladder transitional cell carcinoma: To further validate the TSP4, MMP2, and MMP9 associations in human BC tumours, we analysed the correlations among TSP4, MMP2 and MMP9 expression in human BC tumours by analysing The Cancer Genome Atlas (TCGA) database for urothelial bladder carcinoma datasets on the GEPIA2 web server.