Indeed, loading of human leukemic THP-1 cells (Figure 5B), as well as murine glioblastoma GL261 cells (Figure 5C), with C16:0 peptide to enrich gp100 epitope expression on MHC class I increased killing of tumor cells by gp100-specific MHC class I-restricted CD8+ T cells. This evidence concerns the gene PMEL and glioblastoma.