We transfected miR-2276-5p mimics and negative control (NC) miRNA into the LN229 and U87 human glioma cell lines and found that when miR-2276-5p was ectopically highly expressed in LN229 and U87 glioma cells, the expression of RAB13 mRNA in cells was decreased, as evaluated by RT-PCR (Figure 3B). This evidence concerns the gene RAB13 and central nervous system cancer.