For example, Rab37 controls the exocytosis of TIMP1 to inhibit inactivated MMP9 and thereby suppresses lung cancer metastasis and controls the exocytosis of TIMP2 to inhibit inactivated MMP2 in nasopharyngeal carcinoma (Li et al., 2018; Wang et al., 2018). The gene discussed is RAB37; the disease is lung cancer.