ILK and central nervous system cancer: Therefore, to explore the function of MTORT1, we used microarrays to identify downstream genes of MTORT1. The top five pathways that MTORT1-downstream genes were involved in were production of nitric oxide and reactive oxygen species in macrophages, Gq signaling, glioma invasiveness signaling, FGF signaling, and ILK signaling (Figure 2E).