Therefore, to explore the function of MTORT1, we used microarrays to identify downstream genes of MTORT1. The top five pathways that MTORT1-downstream genes were involved in were production of nitric oxide and reactive oxygen species in macrophages, Gq signaling, glioma invasiveness signaling, FGF signaling, and ILK signaling (Figure 2E). The gene discussed is ILK; the disease is glioma.