GO enrichment analysis showed us that PHF19 is mainly enriched in biological processes related to chromosome activation in biological processes, such as chromosome segregation, nuclear division, etc. And the KEGG pathway analysis indicated that PHF19 was most enriched in 12 pathways, such as cell cycle, DNA replication, p53 signaling, small lung cancer, pancreatic cancer. This evidence concerns the gene TP53 and familial pancreatic carcinoma.