Among different tumors, PHF19 was found to be significantly up-regulated in tumor tissues, which is considered to be closely related to the poor prognosis of patients, such as gastric cancer, melanoma, liver cancer, glioblastoma (Cai et al., 2018; Deng et al., 2018; Ghislin et al., 2012; Wang et al., 2020). Here, PHF19 is linked to melanoma.