NMU and NTS receptors, which belong to G-protein-coupled receptor (GPCR) families, were found to be expressed on the membrane of immune cells including T cells, B cells, macrophages, dendritic cells, mast cells, and on tumour cells (Hedrick et al., 2000; Kim et al., 2006; Magazin et al., 2004; Saada et al., 2012). Here, NMU is linked to neoplasm.