Linear regressions revealed a negative relationship between genetic risk for severe COVID‐19 and levels of TNF‐α [β = −0.065 (−0.105, −0.025), P = 0.001, PFDR = 0.035, R2 = 0.009], vascular endothelial growth factor D [VEGF‐D; β = −0.072 (−0.118, −0.026), P = 0.002, PFDR = 0.035, R2 = 0.017] and IFN‐γ [β = −0.137 (−0.232, −0.042), P = 0.005, PFDR = 0.058, R2 = 0.018](Figure 2). This evidence concerns the gene TNF and COVID-19.