HSPA5 and type 1 diabetes mellitus: BB-Cl-amidine treatment was associated with decreased citrullination levels in the pancreas as demonstrated by LC-MS/MS and western blotting with anti-citrulline Ab, as well as decreased levels of circulating autoantibodies against citrullinated GRP78, a known citrullinated autoantigen in T1D (as outlined above, Table 4) (15, 16).