As shown in Table 1, patients with FA had significantly higher serum IgE levels (p = 0.00003) whereas serological expression of C-reactive protein (CRP), eosinophilic cationic protein (ECP), TNF, tryptase, histamine and diaminooxidase (DAO) as well as leukocyte counts were not different between patients with and without FA. The gene discussed is TNF; the disease is Friedreich ataxia.