RNASE3 and Friedreich ataxia: As shown in Table 1, patients with FA had significantly higher serum IgE levels (p = 0.00003) whereas serological expression of C-reactive protein (CRP), eosinophilic cationic protein (ECP), TNF, tryptase, histamine and diaminooxidase (DAO) as well as leukocyte counts were not different between patients with and without FA.