First, human U1-70K gene was found to accumulate in several cancer-types such as breast cancer (breast tumor luminal, HER2 positive breast carcinoma and triple-negative breast cancer), colon cancer (colon adenocarcinoma and colon mucinous adenocarcinoma) and rectal cancer (rectal cell carcinoma and rectal mucinous adenocarcinoma) (Fig. S9). This evidence concerns the gene ERBB2 and breast neoplasm.