ITGAV and keloid: Considering that one of the primary features of mesenchymal fibroblasts in keloid was abnormal ECM proteins expression including POSTN, and that POSTN-ITGAV;ITGB5 interactions between mesenchymal and other fibroblasts were significantly increased in keloid compared to normal scar, we next explored the function of mesenchymal fibroblasts on keloid fibroblast collagen expression.