By analyzing a cohort of T-ALL patients with outcome information (our unpublished results), we found that HOXA13 or HOXA11 positiveness, alone or in combination, but not the expression of other HOXA genes, such as the previously used biomarker HOXA9, was associated with poor overall and event-free survivals in young adult and pediatric T-ALLs (Fig. 6a and Supplementary Fig. 6a, b). Here, HOXA9 is linked to acute lymphoblastic leukemia.