In addition, there was a relatively high level of interaction between tumor cells and TAMs, particularly via the MHC I-LILRB axis, where MHC class I molecules (B2M and HLA) and LILRB molecules (LILRB1 and LILRB2) were expressed in the respective cells for immunosuppression that supports tumor growth in other cancers18,19 (Supplementary Fig. 16). Here, B2M is linked to neoplasm.