For the POAG group (Additional file 1: Figure S2D–F), the level of ATX was positively correlated with levels of TGF-β1 (Additional file 1: Figure S2D, P = 0.00494) and TGF-β2 (Additional file 1: Figure S2E, P = 0.0408), but not with the level of TGF-β3 (Additional file 1: Figure S2F). The gene discussed is ENPP2; the disease is open-angle glaucoma.