In this study, we generated a human iPSC line (TRNDi012-B, also named as NCATS-CL7989) from patient skin fibroblast (GM00513) which was isolated from a 16-year-old female FOP patient carrying a heterozygous mutation (c.617G > A; p.R206H) in ACVR1 gene. Here, ACVR1 is linked to fibrodysplasia ossificans progressiva.