In turn, these systematic studies have revealed that other common antiviral pathways, such as type I interferons (IFN), do not dominate the early response to COVID-19, probably reflecting evasion of the IFN system by SARS-CoV-2 and the subsequent activation of inflammatory cascades (Hadjadj et al., 2020; Yang et al., 2020). This evidence concerns the gene IFNA1 and COVID-19.