As expected, several advanced nanomedicines involving nucleic acids and vaccines have been processed in clinical trials, such as mRNA nanovaccine (lipo-MERIT) for melanoma (NCT02410733), anti-EGFR bispecific antibody minicells with microRNA for mesothelioma and non-small cell lung cancer (NCT02369198) and autologous cell vaccines for breast cancer (NCT00317603) [44]. This evidence concerns the gene EGFR and non-small cell lung carcinoma.