More important, iPS cells share the similar transcriptome profiles and release the mimic antigens similar to tumor cells due to their apoptosis induced by the enhanced photodynamic therapy, recruited a stronger anti-tumor immune response, improving dendritic cells matured, enhanced the amounts of CD4+ (27.8%) and CD8+ (46.2%)T cells infiltrated into tumor tissues, decreased the amount of T regulation cells, markedly inhibited tumor growth and metastasis. Here, CD4 is linked to neoplasm.