GZMB and posterior cortical atrophy: Interestingly, GRβ, an alternative splicing isoform of GR that does not bind glucocorticoids (Timmermans et al. 2019) possessed the ability to modify the growth of PCa cells, as its depletion decreased PCa cell proliferation (Ligr et al. 2012), suggesting that the GRβ could modulate the tumor suppressor capability of the full-length GR in PCa.