MYL3 and hypertrophy: For example, the likely pathogenic variant (p.Ala57Asp) in MYL3 gene variant is seen in a homozygous state in a 44 years old Qatari HCM patient with obstructive hypertrophy, was reported earlier in a 49 years old Tunisian HCM patient (Jaafar et al., 2015) and interestingly both patients had atrial fibrillation along with the hypertrophy.