The study of incident T2DM conducted among Indian Asians and Europeans showed a 2.5 times higher adjusted risk among Indian Asians than Europeans, and five loci includingABCG1,PHOSPHO1,SOCS3,SREBF1, andTXNIP were associated with incident T2DM among Indian Asians and replicated among Europeans81. This evidence concerns the gene SOCS3 and type 2 diabetes mellitus.