EGFR and lung adenocarcinoma: As reported, in lung adenocarcinoma patients in China, the mutation rate of EGFR gene was 59.04% in Jiaxing [18], 48.7% in Shenzhen [19], 48.9% in Chongqing [20], 52.8% in Hangzhou [21], 47.15% in southern Anhui [22], and 41.04% in Shandong [23].