LncRNA MALAT1, miRNA-33, CXCR4, and TGF-β signaling have all been reported to contribute to bone metastases of NSCLC (Liu et al., 2016; Popper, 2016; Liao et al., 2018; Yang et al., 2019). The gene discussed is MALAT1; the disease is non-small cell lung carcinoma.